WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 561371
CAS#: 1643593-29-6
Description: Ianthelliformisamine B TFA is an antibiotic enhancer against resistant Gram-negative bacteria.
MedKoo Cat#: 561371
Name: Ianthelliformisamine B TFA
CAS#: 1643593-29-6
Chemical Formula: C26H35Br2F9N4O8
Exact Mass:
Molecular Weight: 862.38
Elemental Analysis: C, 36.21; H, 4.09; Br, 18.53; F, 19.83; N, 6.50; O, 14.84
Synonym: Ianthelliformisamine B TFA; Ianthelliformisamine-B TFA; IanthelliformisamineB TFA; Ianthelliformisamine B TFA salt;
IUPAC/Chemical Name: (E)-N-(3-((4-aminobutyl)amino)propyl)-3-(3,5-dibromo-4-methoxyphenyl)acrylamide bis(2,2,2-trifluoroacetate)
InChi Key: FKIKCFCKBQMKRB-TXOOBNKBSA-N
InChi Code: InChI=1S/C17H25Br2N3O2.2C2HF3O2/c1-24-17-14(18)11-13(12-15(17)19)5-6-16(23)22-10-4-9-21-8-3-2-7-20;2*3-2(4,5)1(6)7/h5-6,11-12,21H,2-4,7-10,20H2,1H3,(H,22,23);2*(H,6,7)/b6-5+;;
SMILES Code: O=C(NCCCNCCCCN)/C=C/C1=CC(Br)=C(OC)C(Br)=C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
1: Pieri C, Borselli D, Di Giorgio C, De Méo M, Bolla JM, Vidal N, Combes S, Brunel JM. New Ianthelliformisamine derivatives as antibiotic enhancers against resistant Gram-negative bacteria. J Med Chem. 2014 May 22;57(10):4263-72. doi: 10.1021/jm500194e. Epub 2014 May 13. PubMed PMID: 24801877.
2: Khan FA, Ahmad S, Kodipelli N, Shivange G, Anindya R. Syntheses of a library of molecules on the marine natural product ianthelliformisamines platform and their biological evaluation. Org Biomol Chem. 2014 Jun 21;12(23):3847-65. doi: 10.1039/c3ob42537a. PubMed PMID: 24668192.
3: Xu M, Davis RA, Feng Y, Sykes ML, Shelper T, Avery VM, Camp D, Quinn RJ. Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis. J Nat Prod. 2012 May 25;75(5):1001-5. doi: 10.1021/np300147d. Epub 2012 Apr 19. PubMed PMID: 22515429.