A 76154

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MedKoo CAT#: 571189

CAS#: 136989-30-5

Description: A 76154 is a novel octapeptide (leutenizing hormone releasing hormone) LHRH antagonist.

Price and Availability

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Pricing updated 2020-08-12. Prices are subject to change without notice.

A 76154 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 571189
Name: A 76154
CAS#: 136989-30-5
Chemical Formula: C70H93FN12O12
Exact Mass: 1312.702
Molecular Weight: 1313.58
Elemental Analysis: C, 64.01; H, 7.14; F, 1.45; N, 12.80; O, 14.62

Synonym: A 76154; A-76154; A76154

IUPAC/Chemical Name: N-((5R,8S,11R,15S,18R)-18-amino-1-(4-fluorophenyl)-8-(hydroxymethyl)-15-isobutyl-10-(N6-isopropyl-L-lysyl-L-prolyl)-11-methyl-13-(methyl-L-tyrosyl)-5-(naphthalen-1-ylmethyl)-3,6,9,12,14,17-hexaoxo-4,7,10,13,16-pentaazadocosan-22-yl)nicotinamide


InChi Code: InChI=1S/C70H93FN12O12/c1-43(2)38-58(79-63(88)54(72)21-9-12-36-77-62(87)50-19-14-34-75-41-50)68(93)83(67(92)57(74-6)39-47-26-31-52(85)32-27-47)65(90)45(5)82(70(95)60-23-15-37-81(60)66(91)55(73)22-10-11-35-76-44(3)4)69(94)59(42-84)80-64(89)56(40-49-18-13-17-48-16-7-8-20-53(48)49)78-61(86)33-28-46-24-29-51(71)30-25-46/h7-8,13-14,16-20,24-27,29-32,34,41,43-45,54-60,74,76,84-85H,9-12,15,21-23,28,33,35-40,42,72-73H2,1-6H3,(H,77,87)(H,78,86)(H,79,88)(H,80,89)/t45-,54-,55+,56-,57+,58+,59+,60+/m1/s1

SMILES Code: O=C(NCCCC[C@@H](N)C(N[C@@H](CC(C)C)C(N(C([C@H](CC1=CC=C(O)C=C1)NC)=O)C([C@@H](C)N(C([C@H]2N(C([C@H](CCCCNC(C)C)N)=O)CCC2)=O)C([C@H](CO)NC([C@@H](CC3=C4C=CC=CC4=CC=C3)NC(CCC5=CC=C(F)C=C5)=O)=O)=O)=O)=O)=O)C6=CN=CC=C6

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Haviv F, Fitzpatrick TD, Nichols CJ, Bush EN, Diaz G, Bammert G, Nguyen AT, Johnson ES, Knittle J, Greer J. In vitro and in vivo activities of reduced-size antagonists of luteinizing hormone-releasing hormone. J Med Chem. 1994 Mar 4;37(5):701-5. PubMed PMID: 7510341.