A 69992

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MedKoo CAT#: 571170

CAS#: 138921-14-9

Description: A 69992 is an HIV anti-infective nucleoside. Its enantiomers (see Synonyms) also show anti-HIV activity.

Price and Availability

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Pricing updated 2020-03-29. Prices are subject to change without notice.

A 69992 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 571170
Name: A 69992
CAS#: 138921-14-9
Chemical Formula: C11H14TN5O3
Exact Mass: 267.1257
Molecular Weight: 267.28
Elemental Analysis: C, 49.43; H, 6.41; N, 26.20; O, 17.96

Synonym: A 69992; A-69992; A69992; Abbott 69992; A 75962; A-75962; A75962; A 75179; A75179; A-75179;

IUPAC/Chemical Name: 6H-Purin-6-one-8-t,2-amino-9-(2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro-, (1alpha,2beta,3alpha)-(+-)-


InChi Code: InChI=1S/C11H15N5O3/c12-11-14-9-8(10(19)15-11)13-4-16(9)7-1-5(2-17)6(7)3-18/h4-7,17-18H,1-3H2,(H3,12,14,15,19)/t5-,6-,7-/m0/s1/i4T

SMILES Code: O=C1NC(N)=NC2=C1N=C([3H])N2[C@@H]3[C@@H](CO)[C@H](CO)C3

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Thomas SB, Surber BW. Preparative separation and analysis of the enantiomers of [3H]Abbott-69992, an HIV anti-infective nucleoside, by ligand exchange high-performance liquid chromatography. J Chromatogr. 1991 Nov 22;586(2):265-70. PubMed PMID: 1810972.

2: Kohlbrenner WE, Carter CD, Fesik SW, Norbeck DW, Erickson J. Efficiency of phosphorylation of the cyclobut-G (A-69992) enantiomers by HSV-1 thymidine kinase does not correlate with their anti-herpesvirus activity. Biochem Pharmacol. 1990 Dec 1;40(11):R5-10. PubMed PMID: 2176497.