A 55453

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571141

CAS#: 89687-06-9

Description: A 55453 is a radiated ionophore used as a high-affinity alpha 1-adrenergic receptor probe. It is a ligand that binds reversibly to rat hepatic plasma membranes with high affinity; thus it can be useful for the molecular characterization of alpha 1-adrenergic receptors in tissues.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-03-29. Prices are subject to change without notice.

A 55453 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 571141
Name: A 55453
CAS#: 89687-06-9
Chemical Formula: C25H32N6O3
Exact Mass: 464.2536
Molecular Weight: 464.57
Elemental Analysis: C, 64.64; H, 6.94; N, 18.09; O, 10.33

Synonym: A55453; A 55453; A-55453

IUPAC/Chemical Name: Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(5-(4-aminophenyl)-1-oxopentyl)-


InChi Code: InChI=1S/C25H32N6O3/c1-33-21-15-19-20(16-22(21)34-2)28-25(29-24(19)27)31-13-11-30(12-14-31)23(32)6-4-3-5-17-7-9-18(26)10-8-17/h7-10,15-16H,3-6,11-14,26H2,1-2H3,(H2,27,28,29)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Dickinson KE, Leeb-Lundberg LM, Heald SL, Wikberg JE, DeBernardis JF, Caron MG, Lefkowitz RJ. Photoaffinity cross-linking of a radioiodinated probe, 125I-A55453, into alpha 1-adrenergic receptors. Mol Pharmacol. 1984 Sep;26(2):187-95. PubMed PMID: 6090880.