15-Hexadecynoic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561300

CAS#: 99208-90-9

Description: 15-Hexadecynoic acid is a chemical probe for SCRIB palmitoylation and palmitoyl acyltransferases (PATs).

Price and Availability




15-Hexadecynoic acid is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 561300
Name: 15-Hexadecynoic acid
CAS#: 99208-90-9
Chemical Formula: C16H28O2
Exact Mass: 252.2089
Molecular Weight: 252.4
Elemental Analysis: C, 76.14; H, 11.18; O, 12.68

Synonym: 15-Hexadecynoic acid; 15 Hexadecynoic acid; 15Hexadecynoic acid

IUPAC/Chemical Name: Hexadec-15-ynoic acid


InChi Code: InChI=1S/C16H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h1H,3-15H2,(H,17,18)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


1: Chan P, Han X, Zheng B, DeRan M, Yu J, Jarugumilli GK, Deng H, Pan D, Luo X, Wu X. Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway. Nat Chem Biol. 2016 Apr;12(4):282-9. doi: 10.1038/nchembio.2036. Epub 2016 Feb 22. PubMed PMID: 26900866; PubMed Central PMCID: PMC4798901.

2: Ebersole B, Petko J, Levenson R. Bioorthogonal click chemistry to assay mu-opioid receptor palmitoylation using 15-hexadecynoic acid and immunoprecipitation. Anal Biochem. 2014 Apr 15;451:25-7. doi: 10.1016/j.ab.2014.01.008. Epub 2014 Jan 23. PubMed PMID: 24463015; PubMed Central PMCID: PMC3969759.

3: Aitken AE, Roman LJ, Loughran PA, de la Garza M, Masters BS. Expressed CYP4A4 metabolism of prostaglandin E(1) and arachidonic acid. Arch Biochem Biophys. 2001 Sep 15;393(2):329-38. PubMed PMID: 11556821.

4: Shak S, Reich NO, Goldstein IM, Ortiz de Montellano PR. Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Suicidal inactivation by acetylenic fatty acids. J Biol Chem. 1985 Oct 25;260(24):13023-8. PubMed PMID: 2997155.