C012 Dihydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561275

CAS#: 1219163-50-4

Description: C012 Dihydrochloride is a novel small molecule compound which sensitized BRAF wild-type melanoma cells to vemurafenib. C012 Dihydrochloride significantly reduced melanoma cell viability, with limited toxicity for normal human fibroblasts.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2021-01-28. Prices are subject to change without notice.

C012 Dihydrochloride is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 561275
Name: C012 Dihydrochloride
CAS#: 1219163-50-4
Chemical Formula: C23H30Cl2N4O
Exact Mass: 448.1797
Molecular Weight: 449.42
Elemental Analysis: C, 61.47; H, 6.73; Cl, 15.78; N, 12.47; O, 3.56

Synonym: C012 Dihydrochloride; C-012 Dihydrochloride; C 012 Dihydrochloride; C012 2HCl; C 012 2HCl; C-012 2HCl;

IUPAC/Chemical Name: {2-[2-(4-Ethoxy-phenyl)-1,3a,8-triaza-cyclopenta[a]inden-8-yl]-ethyl}-diethyl-amine dihydrochloride


InChi Code: InChI=1S/C23H28N4O.2ClH/c1-4-25(5-2)15-16-26-21-9-7-8-10-22(21)27-17-20(24-23(26)27)18-11-13-19(14-12-18)28-6-3;;/h7-14,17H,4-6,15-16H2,1-3H3;2*1H


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Sutton SK, Carter DR, Kim P, et al. A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner. Oncotarget. 2016;7(32):52166-52178. doi:10.18632/oncotarget.10700.