BzDANP

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561202

CAS#: 1994258-88-6

Description: BzDANP is a modulator of pre-miR-29a maturation by Dicer. BzDANP binding to the bulged site in the vicinity of the Dicer cleavage site could be a potential modulator for the maturation of pre-miRNA.


Price and Availability

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BzDANP is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561202
Name: BzDANP
CAS#: 1994258-88-6
Chemical Formula: C18H24N6
Exact Mass: 324.2062
Molecular Weight: 324.43
Elemental Analysis: C, 66.64; H, 7.46; N, 25.90


Synonym: BzDANP; Benzo-DANP; Benzo DANP; BenzoDANP

IUPAC/Chemical Name: 3,6-Bis(3-aminopropylamino)-benzo[c][1,8]naphthyridine

InChi Key: WJNRGGQXDIDZAN-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H24N6/c19-9-3-11-21-16-8-7-15-13-5-1-2-6-14(13)17(22-12-4-10-20)24-18(15)23-16/h1-2,5-8H,3-4,9-12,19-20H2,(H2,21,22,23,24)

SMILES Code: NCCCNC1=NC2=NC(NCCCN)=CC=C2C3=CC=CC=C13


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Murata A, Otabe T, Zhang J, Nakatani K. BzDANP, a Small-Molecule Modulator of Pre-miR-29a Maturation by Dicer. ACS Chem Biol. 2016 Oct 21;11(10):2790-2796. Epub 2016 Aug 25. PubMed PMID: 27536863.