BzDANP

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561202

CAS#: 1994258-88-6

Description: BzDANP is a modulator of pre-miR-29a maturation by Dicer. BzDANP binding to the bulged site in the vicinity of the Dicer cleavage site could be a potential modulator for the maturation of pre-miRNA.

Chemical Structure

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BzDANP
CAS# 1994258-88-6
Instruction

Theoretical Analysis

MedKoo Cat#: 561202
Name: BzDANP
CAS#: 1994258-88-6
Chemical Formula: C18H24N6
Exact Mass: 324.21
Molecular Weight: 324.430
Elemental Analysis: C, 66.64; H, 7.46; N, 25.90

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: BzDANP; Benzo-DANP; Benzo DANP; BenzoDANP

IUPAC/Chemical Name: 3,6-Bis(3-aminopropylamino)-benzo[c][1,8]naphthyridine

InChi Key: WJNRGGQXDIDZAN-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H24N6/c19-9-3-11-21-16-8-7-15-13-5-1-2-6-14(13)17(22-12-4-10-20)24-18(15)23-16/h1-2,5-8H,3-4,9-12,19-20H2,(H2,21,22,23,24)

SMILES Code: NCCCNC1=NC2=NC(NCCCN)=CC=C2C3=CC=CC=C13

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 324.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Murata A, Otabe T, Zhang J, Nakatani K. BzDANP, a Small-Molecule Modulator of Pre-miR-29a Maturation by Dicer. ACS Chem Biol. 2016 Oct 21;11(10):2790-2796. Epub 2016 Aug 25. PubMed PMID: 27536863.