K252c
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MedKoo CAT#: 540243

CAS#: 85753-43-1

Description: K252c is a staurosporine analog and inhibitor of PKC and PKA. It inhibits proliferation of human cytomegalovirus and induces apoptosis in cancer cells.


Chemical Structure

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K252c
CAS# 85753-43-1

Theoretical Analysis

MedKoo Cat#: 540243
Name: K252c
CAS#: 85753-43-1
Chemical Formula: C20H13N3O
Exact Mass: 311.11
Molecular Weight: 311.340
Elemental Analysis: C, 77.16; H, 4.21; N, 13.50; O, 5.14

Price and Availability

Size Price Availability Quantity
5mg USD 600 2 Weeks
10mg USD 1050 2 Weeks
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Synonym: staurosporine aglycone; K252c; SD 1825; SD-1825; SD1825;

IUPAC/Chemical Name: 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one

InChi Key: MEXUTNIFSHFQRG-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H13N3O/c24-20-17-12(9-21-20)15-10-5-1-3-7-13(10)22-18(15)19-16(17)11-6-2-4-8-14(11)23-19/h1-8,22-23H,9H2,(H,21,24)

SMILES Code: O=C1C2=C(C3=CC=CC=C3N4)C4=C5NC6=CC=CC=C6C5=C2CN1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 311.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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