2''-Galloylhyperin
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 540152

CAS#: 53209-27-1

Description: 2''-Galloylhyperin found in Pyrola. It increases ruminal fiber fermentability by formed wall-bound lignin in primary maize cell walls.


Chemical Structure

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2''-Galloylhyperin
CAS# 53209-27-1

Theoretical Analysis

MedKoo Cat#: 540152
Name: 2''-Galloylhyperin
CAS#: 53209-27-1
Chemical Formula: C28H24O16
Exact Mass: 616.11
Molecular Weight: 616.480
Elemental Analysis: C, 54.55; H, 3.92; O, 41.52

Price and Availability

Size Price Availability Quantity
5mg USD 250 2 Weeks
10mg USD 450 2 Weeks
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Synonym: FT-0689359; FT0689359; FT 0689359; Q-100605; Q100605; Q 100605; 2''-Galloylhyperin

IUPAC/Chemical Name: (2S,3R,4S,5R,6R)-2-((2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl 3,4,5-trihydroxybenzoate

InChi Key: PXGWEUQZDRUMRE-UNZYZCBSSA-N

InChi Code: InChI=1S/C28H24O16/c29-8-18-21(37)23(39)26(43-27(40)10-4-15(34)20(36)16(35)5-10)28(42-18)44-25-22(38)19-14(33)6-11(30)7-17(19)41-24(25)9-1-2-12(31)13(32)3-9/h1-7,18,21,23,26,28-37,39H,8H2/t18-,21+,23+,26-,28+/m1/s1

SMILES Code: O=C(O[C@H]1[C@H](OC2=C(C3=CC=C(O)C(O)=C3)OC4=C(C(O)=CC(O)=C4)C2=O)O[C@H](CO)[C@H](O)[C@@H]1O)C5=CC(O)=C(O)C(O)=C5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 616.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Wang P, Gao YM, Sun X, Guo N, Li J, Wang W, Yao LP, Fu YJ. Hepatoprotective effect of 2'-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway. Food Chem Toxicol. 2017 Apr;102:129-142. doi: 10.1016/j.fct.2017.02.016. Epub 2017 Feb 16. PubMed PMID: 28213291.

2: Li XH, Wang JX, Wang XY. [Determination of 2"-O-galloylhyperin in Pyrola calliantha H. Andres]. Zhongguo Zhong Yao Za Zhi. 1994 Feb;19(2):103-4, 127. Chinese. PubMed PMID: 8011130.

3: Zhou D, Jin Y, Yao F, Duan Z, Wang Q, Liu J. Validated LC-MS/MS method for the simultaneous determination of hyperoside and 2''-O-galloylhyperin in rat plasma: application to a pharmacokinetic study in rats. Biomed Chromatogr. 2014 Aug;28(8):1057-63. doi: 10.1002/bmc.3117. Epub 2013 Dec 21. PubMed PMID: 24375731.

4: Zhang DY, Yao XH, Duan MH, Luo M, Zhao CJ, Zu YG, Fu YJ. An effective homogenate-assisted negative pressure cavitation extraction for the determination of phenolic compounds in pyrola by LC-MS/MS and the evaluation of its antioxidant activity. Food Funct. 2015 Oct;6(10):3323-33. doi: 10.1039/c5fo00727e. Epub 2015 Aug 10. PubMed PMID: 26256648.

5: Yao XH, Zhang DY, Luo M, Jin S, Zu YG, Efferth T, Fu YJ. Negative pressure cavitation-microwave assisted preparation of extract of Pyrola incarnata Fisch. rich in hyperin, 2'-O-galloylhyperin and chimaphilin and evaluation of its antioxidant activity. Food Chem. 2015 Feb 15;169:270-6. doi: 10.1016/j.foodchem.2014.07.115. Epub 2014 Aug 5. PubMed PMID: 25236226.