WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 540152
CAS#: 53209-27-1
Description: 2''-Galloylhyperin found in Pyrola. It increases ruminal fiber fermentability by formed wall-bound lignin in primary maize cell walls.
MedKoo Cat#: 540152
Name: 2''-Galloylhyperin
CAS#: 53209-27-1
Chemical Formula: C28H24O16
Exact Mass: 616.1064
Molecular Weight: 616.48
Elemental Analysis: C, 54.55; H, 3.92; O, 41.52
Synonym: FT-0689359; FT0689359; FT 0689359; Q-100605; Q100605; Q 100605; 2''-Galloylhyperin
IUPAC/Chemical Name: (2S,3R,4S,5R,6R)-2-((2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl 3,4,5-trihydroxybenzoate
InChi Key: PXGWEUQZDRUMRE-UNZYZCBSSA-N
InChi Code: InChI=1S/C28H24O16/c29-8-18-21(37)23(39)26(43-27(40)10-4-15(34)20(36)16(35)5-10)28(42-18)44-25-22(38)19-14(33)6-11(30)7-17(19)41-24(25)9-1-2-12(31)13(32)3-9/h1-7,18,21,23,26,28-37,39H,8H2/t18-,21+,23+,26-,28+/m1/s1
SMILES Code: O=C(O[C@H]1[C@H](OC2=C(C3=CC=C(O)C(O)=C3)OC4=C(C(O)=CC(O)=C4)C2=O)O[C@H](CO)[C@H](O)[C@@H]1O)C5=CC(O)=C(O)C(O)=C5
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 616.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Wang P, Gao YM, Sun X, Guo N, Li J, Wang W, Yao LP, Fu YJ. Hepatoprotective effect of 2'-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway. Food Chem Toxicol. 2017 Apr;102:129-142. doi: 10.1016/j.fct.2017.02.016. Epub 2017 Feb 16. PubMed PMID: 28213291.
2: Li XH, Wang JX, Wang XY. [Determination of 2"-O-galloylhyperin in Pyrola calliantha H. Andres]. Zhongguo Zhong Yao Za Zhi. 1994 Feb;19(2):103-4, 127. Chinese. PubMed PMID: 8011130.
3: Zhou D, Jin Y, Yao F, Duan Z, Wang Q, Liu J. Validated LC-MS/MS method for the simultaneous determination of hyperoside and 2''-O-galloylhyperin in rat plasma: application to a pharmacokinetic study in rats. Biomed Chromatogr. 2014 Aug;28(8):1057-63. doi: 10.1002/bmc.3117. Epub 2013 Dec 21. PubMed PMID: 24375731.
4: Zhang DY, Yao XH, Duan MH, Luo M, Zhao CJ, Zu YG, Fu YJ. An effective homogenate-assisted negative pressure cavitation extraction for the determination of phenolic compounds in pyrola by LC-MS/MS and the evaluation of its antioxidant activity. Food Funct. 2015 Oct;6(10):3323-33. doi: 10.1039/c5fo00727e. Epub 2015 Aug 10. PubMed PMID: 26256648.
5: Yao XH, Zhang DY, Luo M, Jin S, Zu YG, Efferth T, Fu YJ. Negative pressure cavitation-microwave assisted preparation of extract of Pyrola incarnata Fisch. rich in hyperin, 2'-O-galloylhyperin and chimaphilin and evaluation of its antioxidant activity. Food Chem. 2015 Feb 15;169:270-6. doi: 10.1016/j.foodchem.2014.07.115. Epub 2014 Aug 5. PubMed PMID: 25236226.
