YU142670
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526349

CAS#: 133847-06-0

Description: YU142670 is a novel selective inhibitor against OCRL1/INPP5F and OCRL2/INPP5B by targeting OCRL catalytic domain.


Chemical Structure

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YU142670
CAS# 133847-06-0

Theoretical Analysis

MedKoo Cat#: 526349
Name: YU142670
CAS#: 133847-06-0
Chemical Formula: C8H5N5S
Exact Mass: 203.03
Molecular Weight: 203.223
Elemental Analysis: C, 47.28; H, 2.48; N, 34.46; S, 15.78

Price and Availability

Size Price Availability Quantity
25mg USD 850 2 Weeks
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Synonym: YU142670, YU 142670, YU-142670

IUPAC/Chemical Name: 3-(4-Pyridinyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole

InChi Key: HRBYAJQMVADJHW-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H5N5S/c1-3-9-4-2-6(1)7-11-12-8-13(7)10-5-14-8/h1-5H

SMILES Code: C12=NN=C(C3=CC=NC=C3)N1N=CS2

Appearance: White to light brown solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 203.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Pirruccello M, Nandez R, Idevall-Hagren O, Alcazar-Roman A, Abriola L, Berwick SA, Lucast L, Morel D, De Camilli P. Identification of inhibitors of inositol 5-phosphatases through multiple screening strategies. ACS Chem Biol. 2014 Jun 20;9(6):1359-68. doi: 10.1021/cb500161z. Epub 2014 May 1. PubMed PMID: 24742366; PubMed Central PMCID: PMC4076014.