WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532774

CAS#: 867164-40-7

Description: TRC051384 is a inducer of heat shock protein Hsp70. It reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke. TRC051384 enhances Hsp72 expression in neurons and glial cells.

Chemical Structure

CAS# 867164-40-7

Theoretical Analysis

MedKoo Cat#: 532774
Name: TRC051384
CAS#: 867164-40-7
Chemical Formula: C25H31N5O4
Exact Mass: 465.24
Molecular Weight: 465.550
Elemental Analysis: C, 64.50; H, 6.71; N, 15.04; O, 13.75

Price and Availability

Size Price Availability Quantity
50mg USD 550
100mg USD 950
200mg USD 1650
500mg USD 2650
1g USD 3450
2g USD 5450
5g USD 8950
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Synonym: TRC051384; TRC 051384; TRC-051384.

IUPAC/Chemical Name: N-[2-(4-Morpholinyl)ethyl]-N'-[4-[3-[6-(4-morpholinyl)-2-pyridinyl]-1-oxo-2-propen-1-yl]phenyl]urea


InChi Code: InChI=1S/C25H31N5O4/c31-23(9-8-21-2-1-3-24(27-21)30-14-18-34-19-15-30)20-4-6-22(7-5-20)28-25(32)26-10-11-29-12-16-33-17-13-29/h1-9H,10-19H2,(H2,26,28,32)/b9-8+


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 465.550000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Mohanan et al (2011) Delayed intervention in experimental stroke with TRC051384--a small molecule HSP70 inducer. Neuropharmacology. 60 991. PMID: 21167846.