WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532614
Description: S22153 is a melatonin receptor antagonist.
MedKoo Cat#: 532614
Chemical Formula: C14H17NOS
Exact Mass: 247.1031
Molecular Weight: 247.36
Elemental Analysis: C, 67.98; H, 6.93; N, 5.66; O, 6.47; S, 12.96
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: S22153; S 22153; S-22153.
IUPAC/Chemical Name: N-[2-(5-ethyl-1-benzothiophen-3-yl)ethyl]acetamide
InChi Key: PICRXJDULXLJCZ-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H17NOS/c1-3-11-4-5-14-13(8-11)12(9-17-14)6-7-15-10(2)16/h4-5,8-9H,3,6-7H2,1-2H3,(H,15,16)
SMILES Code: CC(NCCC1=CSC2=CC=C(CC)C=C12)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 247.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Li XM, Beau J, Delagrange P, Mocaër E, Lévi F. Circadian rhythm entrainment with melatonin, melatonin receptor antagonist S22153 or their combination in mice exposed to constant light. J Pineal Res. 2004 Oct;37(3):176-84. PubMed PMID: 15357662.
2: Pitrosky B, Delagrange P, Rettori MC, Pévet P. S22153, a melatonin antagonist, dissociates different aspects of photoperiodic responses in Syrian hamsters. Behav Brain Res. 2003 Jan 22;138(2):145-52. PubMed PMID: 12527445.