WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530629

CAS#: 314263-42-8

Description: DCG04 is a multivalent ligand for the mannose-6-phosphate receptor for endolysosomal targeting of an activity-based probe. DCG-04 is an activity-based probe for cysteine cathepsins, enabled fluorescent readout of its receptor-targeting properties. The resulting M6P-cluster-BODIPY-DCG-04 probe was shown to efficiently label cathepsins in cell lysates as well as in live cells.

Price and Availability


USD 5950

USD 7950

USD 14650

DCG04, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 530629
Name: DCG04
CAS#: 314263-42-8
Chemical Formula: C43H66N8O11S
Exact Mass: 902.4572
Molecular Weight: 903.106
Elemental Analysis: C, 57.19; H, 7.37; N, 12.41; O, 19.49; S, 3.55

Synonym: DCG04; DCG-04; DCG 04.

IUPAC/Chemical Name: ethyl 3-(((4S,7S,17S)-17-carbamoyl-7-(4-hydroxybenzyl)-2-methyl-5,8,15,23-tetraoxo-27-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,16,22-tetraazaheptacosan-4-yl)carbamoyl)oxirane-2-carboxylate


InChi Code: InChI=1S/C43H66N8O11S/c1-4-61-42(59)37-36(62-37)41(58)49-29(22-25(2)3)40(57)48-30(23-26-16-18-27(52)19-17-26)39(56)46-21-10-5-6-15-34(54)47-28(38(44)55)12-9-11-20-45-33(53)14-8-7-13-32-35-31(24-63-32)50-43(60)51-35/h16-19,25,28-32,35-37,52H,4-15,20-24H2,1-3H3,(H2,44,55)(H,45,53)(H,46,56)(H,47,54)(H,48,57)(H,49,58)(H2,50,51,60)/t28-,29-,30-,31?,32?,35?,36?,37?/m0/s1


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


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14: Reich M, van Swieten PF, Sommandas V, Kraus M, Fischer R, Weber E, Kalbacher H, Overkleeft HS, Driessen C. Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins. J Leukoc Biol. 2007 Apr;81(4):990-1001. Epub 2007 Jan 29. PubMed PMID: 17261546.

15: Rooney HC, Van't Klooster JW, van der Hoorn RA, Joosten MH, Jones JD, de Wit PJ. Cladosporium Avr2 inhibits tomato Rcr3 protease required for Cf-2-dependent disease resistance. Science. 2005 Jun 17;308(5729):1783-6. Epub 2005 Apr 21. Erratum in: Science. 2005 Oct 7;310(5745):54. PubMed PMID: 15845874.

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