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MedKoo CAT#: 530618

CAS#: 1820763-99-2

Description: BCM-599 is a HBV capsid assembly inhibitor. BCM-599 could be utilized as an effective combination treatment against HBV infection. BCM-599 showed IC50 of 0.88 μM and CC50 of 144 μM in HepG2.2.15 cells. BCM-599 decreased both intracellular and extracellular viral DNA levels without affecting the pgRNA level; moreover, interestingly, at the concentration of 0.88 μM, BCM-599 reduced the intracellular capsid level by 51% while increased the amount of free core protein dimer by 5-fold.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-19. Prices are subject to change without notice.

BCM-599 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 530618
Name: BCM-599
CAS#: 1820763-99-2
Chemical Formula: C14H10Cl2FN3O2
Exact Mass: 341.0134
Molecular Weight: 342.1514
Elemental Analysis: C, 49.15; H, 2.95; Cl, 20.72; F, 5.55; N, 12.28; O, 9.35

Synonym: BCM-599; BCM 599; BCM599.

IUPAC/Chemical Name: N-(2-((2,6-dichloropyridin-3-yl)amino)-2-oxoethyl)-4-fluorobenzamide


InChi Code: InChI=1S/C14H10Cl2FN3O2/c15-11-6-5-10(13(16)20-11)19-12(21)7-18-14(22)8-1-3-9(17)4-2-8/h1-6H,7H2,(H,18,22)(H,19,21)

SMILES Code: FC1=CC=C(C(NCC(NC2=C(Cl)N=C(Cl)C=C2)=O)=O)C=C1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Cho MH, Jeong H, Kim YS, Kim JW, Jung G.
2-amino-N-(2,6-dichloropyridin-3-yl)acetamide derivatives as a novel class of HBV
capsid assembly inhibitor. J Viral Hepat. 2014 Dec;21(12):843-52. doi:
10.1111/jvh.12214. Epub 2013 Dec 25. PubMed PMID: 24372792.