LP-211
new
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532114

CAS#: 1052147-86-0

Description: LP-211 is a a selective agonist of the serotonin 5-HT7 receptor with a Ki value of 0.58 nM at rat cloned 5-HT7 receptors, and >300-fold selectivity over the 5-HT1A receptor.


Price and Availability

Size
Price

50mg
USD 450
500mg
USD 1950
5g
USD 7650
Size
Price

100mg
USD 750
1g
USD 3150
Size
Price

200mg
USD 1250
2g
USD 5450

LP-211, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS docum ents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 532114
Name: LP-211
CAS#: 1052147-86-0
Chemical Formula: C30H34N4O
Exact Mass: 466.2733
Molecular Weight: 466.63
Elemental Analysis: Chemical Formula: C30H34N4O Exact Mass: 466.2733 Molecular Weight: 466.6290 Elemental Analysis: C, 77.22; H, 7.34; N, 12.01; O, 3.43


Synonym: LP-211; LP 211; LP211.

IUPAC/Chemical Name: N-[(4-cyanophenyl)methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide

InChi Key: BQEDZLDNNBDKDS-UHFFFAOYSA-N

InChi Code: InChI=1S/C30H34N4O/c31-23-25-14-16-26(17-15-25)24-32-30(35)13-5-2-8-18-33-19-21-34(22-20-33)29-12-7-6-11-28(29)27-9-3-1-4-10-27/h1,3-4,6-7,9-12,14-17H,2,5,8,13,18-22,24H2,(H,32,35)

SMILES Code: O=C(NCC1=CC=C(C#N)C=C1)CCCCCN2CCN(C3=CC=CC=C3C4=CC=CC=C4)CC2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1: Norouzi-Javidan A, Javanbakht J, Barati F, Fakhraei N, Mohammadi F, Dehpour AR. Effect of 5-HT7 receptor agonist, LP-211, on micturition following spinal cord injury in male rats. Am J Transl Res. 2016 Jun 15;8(6):2525-33. PubMed PMID: 27398137; PubMed Central PMCID: PMC4931148.

2: Demirkaya K, Akgün ÖM, Şenel B, Öncel Torun Z, Seyrek M, Lacivita E, Leopoldo M, Doğrul A. Selective 5-HT7 receptor agonists LP 44 and LP 211 elicit an analgesic effect on formalin-induced orofacial pain in mice. J Appl Oral Sci. 2016 May-Jun;24(3):218-22. doi: 10.1590/1678-775720150563. PubMed PMID: 27383702; PubMed Central PMCID: PMC5022221.