WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532078
CAS#: 874882-93-6 (HCl)
Description: L-741,742 hydrochloride is a potent and highly selective D4 dopamine receptor antagonist, with Ki values of > 1700, 770 and 3.5 nM at cloned human D2, D3 and D4 receptors.
MedKoo Cat#: 532078
Name: L-741,742 hydrochloride
CAS#: 874882-93-6 (HCl)
Chemical Formula: C23H26Cl2N2O
Exact Mass:
Molecular Weight: 417.37
Elemental Analysis: C, 66.19; H, 6.28; Cl, 16.99; N, 6.71; O, 3.83
Related CAS #: 874882-93-6 (HCl) 156337-32-5 (Free Base)
Synonym: L-741,742 hydrochloride; L741742; L 741742; L-741742.
IUPAC/Chemical Name: 5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole hydrochloride
InChi Key: HZRPUQURUAXOHB-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H25ClN2O.ClH/c1-17-22(25-27-23(17)20-7-9-21(24)10-8-20)19-12-15-26(16-13-19)14-11-18-5-3-2-4-6-18;/h2-10,19H,11-16H2,1H3;1H
SMILES Code: CC1=C(C2=CC=C(Cl)C=C2)ON=C1C3CCN(CCC4=CC=CC=C4)CC3.[H]Cl
1: Rowley M, Collins I, Broughton HB, Davey WB, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Ball R, Leeson PD. 4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor. J Med Chem. 1997 Jul 18;40(15):2374-85. PubMed PMID: 9240352.