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MedKoo CAT#: 532077

CAS#: 81226-60-0

Description: L-741,626 is a selective D2 receptor antagonist.

Price and Availability

Size Price Shipping out time Quantity
10mg USD 270 2 Weeks
50mg USD 750 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-07-04. Prices are subject to change without notice.

L-741,626, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 532077
Name: L-741,626
CAS#: 81226-60-0
Chemical Formula: C20H21ClN2O
Exact Mass: 340.1342
Molecular Weight: 340.85
Elemental Analysis: C, 70.48; H, 6.21; Cl, 10.40; N, 8.22; O, 4.69

Synonym: L-741,626; L 741,626; L741,626.

IUPAC/Chemical Name: 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidin-4-ol


InChi Code: InChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Vangveravong S, Taylor M, Xu J, Cui J, Calvin W, Babic S, Luedtke RR, Mach RH. Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626. Bioorg Med Chem. 2010 Jul 15;18(14):5291-300. doi: 10.1016/j.bmc.2010.05.052. PubMed PMID: 20542439; PubMed Central PMCID: PMC2946321.

2: Pillai G, Brown NA, McAllister G, Milligan G, Seabrook GR. Human D2 and D4 dopamine receptors couple through betagamma G-protein subunits to inwardly rectifying K+ channels (GIRK1) in a Xenopus oocyte expression system: selective antagonism by L-741,626 and L-745,870 respectively. Neuropharmacology. 1998 Aug;37(8):983-7. PubMed PMID: 9833627.

3: Bowery BJ, Razzaque Z, Emms F, Patel S, Freedman S, Bristow L, Kulagowski J, Seabrook GR. Antagonism of the effects of (+)-PD 128907 on midbrain dopamine neurones in rat brain slices by a selective D2 receptor antagonist L-741,626. Br J Pharmacol. 1996 Dec;119(7):1491-7. PubMed PMID: 8968560; PubMed Central PMCID: PMC1915834.