Abacavir hydroxyacetate

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MedKoo CAT#: 529107

CAS#: 1446418-48-9 (hydroxyacetate)

Description: Prurisol, also known as abacavir hydroxyacetate and KM-133, is potentially for the treatment of plaque psoriasis

Chemical Structure

Abacavir hydroxyacetate
CAS# 1446418-48-9 (hydroxyacetate)

Theoretical Analysis

MedKoo Cat#: 529107
Name: Abacavir hydroxyacetate
CAS#: 1446418-48-9 (hydroxyacetate)
Chemical Formula: C16H20N6O3
Exact Mass: 344.1597
Molecular Weight: 344.37
Elemental Analysis: C, 55.80; H, 5.85; N, 24.40; O, 13.94

Price and Availability

Size Price Availability Quantity
1.0mg USD 90.0 Ready to ship
5.0mg USD 150.0 Ready to ship
10.0mg USD 250.0 Ready to ship
25.0mg USD 550.0 Ready to ship
50.0mg USD 950.0 Ready to ship
100.0mg USD 1650.0 Ready to ship
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Related CAS #: 136470-78-5 (free base)   136777-48-5 (HCl)   168146-84-7 (succinate)   188062-50-2 (sulfate)   1446418-48-9 (hydroxyacetate)   384380-52-3 (caeboxylate)    

Synonym: KM-133; KM133; KM 133; Prurisol; Abacavir acetate; Abacavir hydroxyacetate;

IUPAC/Chemical Name: ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methyl 2-hydroxyacetate


InChi Code: InChI=1S/C16H20N6O3/c17-16-20-14(19-10-2-3-10)13-15(21-16)22(8-18-13)11-4-1-9(5-11)7-25-12(24)6-23/h1,4,8-11,23H,2-3,5-7H2,(H3,17,19,20,21)/t9-,11+/m1/s1

SMILES Code: O=C(OC[C@@H]1C=C[C@H](N2C=NC3=C(NC4CC4)N=C(N)N=C23)C1)CO

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Biological target: KM-133 is potential treatment for plaque psoriasis.
In vitro activity: TBD
In vivo activity: TBD

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 0.0 0.0

Preparing Stock Solutions

The following data is based on the product molecular weight 344.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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