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MedKoo CAT#: 407404

CAS#: 1223377-83-0

Description: Z118332870 is a potent dual EGFR/BRD4 inhibitor.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-30. Prices are subject to change without notice.

Z118332870 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 407404
Name: Z118332870
CAS#: 1223377-83-0
Chemical Formula: C18H18FN3O3
Exact Mass: 343.1332
Molecular Weight: 343.3584
Elemental Analysis: C, 62.97; H, 5.28; F, 5.53; N, 12.24; O, 13.98

Synonym: Z118332870; Z-118332870; Z 118332870.

IUPAC/Chemical Name: N-[2-(2-Fluorophenoxy)ethyl]-6,7-dimethoxy-4-quinazolinamine


InChi Code: InChI=1S/C18H18FN3O3/c1-23-16-9-12-14(10-17(16)24-2)21-11-22-18(12)20-7-8-25-15-6-4-3-5-13(15)19/h3-6,9-11H,7-8H2,1-2H3,(H,20,21,22)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Allen BK, Mehta S, Ember SW, Schonbrunn E, Ayad N, Schürer SC. Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4. Sci Rep. 2015 Nov 24;5:16924. doi: 10.1038/srep16924. PubMed PMID: 26596901; PubMed Central PMCID: PMC4657038.