ICI 169369

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 531965

CAS#: 85273-95-6

Description: ICI 169369 is a 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta.

Chemical Structure

ICI 169369
CAS# 85273-95-6

Theoretical Analysis

MedKoo Cat#: 531965
Name: ICI 169369
CAS#: 85273-95-6
Chemical Formula: C19H20N2S
Exact Mass: 308.1347
Molecular Weight: 308.44
Elemental Analysis: C, 73.99; H, 6.54; N, 9.08; S, 10.39

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: ICI 169369; ICI169369; ICI-169369.

IUPAC/Chemical Name: N,N-dimethyl-2-(3-phenylquinolin-2-yl)sulfanylethanamine


InChi Code: InChI=1S/C19H20N2S/c1-21(2)12-13-22-19-17(15-8-4-3-5-9-15)14-16-10-6-7-11-18(16)20-19/h3-11,14H,12-13H2,1-2H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 308.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Pires JG, Ramage AG, Jacobs M. ICI 169,369, A 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta. J Auton Pharmacol. 1993 Aug;13(4):249-55. PubMed PMID: 8408095.

2: Nielsen TH, Tfelt-Hansen P. No effect of the 5HT2-antagonist ICI 169,369 on systolic, ergotamine-induced blood pressure changes in man. Pharmacol Toxicol. 1993 Sep;73(3):133-6. PubMed PMID: 8265515.