WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 531846
CAS#: 144576-10-3
Description: Gea 3162 is a potent inhibitor of ADP-induced platelet aggregation in platelet rich plasma (PRP). GEA 3162 stimulates cGMP production in platelets, granulocytes, and polymorphonuclear leukocytes.
MedKoo Cat#: 531846
Name: Gea 3162
CAS#: 144576-10-3
Chemical Formula: C7H6Cl2N4O
Exact Mass: 231.9919
Molecular Weight: 233.05
Elemental Analysis: C, 36.08; H, 2.60; Cl, 30.42; N, 24.04; O, 6.86
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Gea 3162; Gea3162; Gea-3162.
IUPAC/Chemical Name: 1,2,3,4-Oxatriazolium, 5-amino-3-(3,4-dichlorophenyl)-, inner salt
InChi Key: LNALNDHRNONVMD-UHFFFAOYSA-N
InChi Code: InChI=1S/C7H6Cl2N4O/c8-5-2-1-4(3-6(5)9)13-11-7(10)14-12-13/h1-3,13H,(H2,10,11)
SMILES Code: ClC1=CC=C([NH+]2[N-]OC(N)=N2)C=C1Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 233.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Corell, T., et al., . Pharmacology of mesoionic oxatriazole derivatives in blood, cardiovascular and respiratory systems. Polish journal of pharmacology. 46(6): 553-66. PMID: 7542520
2. Karup, G., et al., . Mesoionic oxatriazole derivatives--a new group of NO-donors. Polish journal of pharmacology. 46(6): 541-52. PMID: 7620516
