Vertilmicin Sulfate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527516

CAS#: 857468-21-4

Description: Vertilmicin Sulfate is an aminoglycoside antibiotic potentially for the treatment of bacterial infections.


Price and Availability

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Vertilmicin Sulfate is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 527516
Name: Vertilmicin Sulfate
CAS#: 857468-21-4
Chemical Formula: C44H96N10O34S5
Exact Mass:
Molecular Weight: 1469.59
Elemental Analysis: C, 35.96; H, 6.58; N, 9.53; O, 37.01; S, 10.91


Synonym: Vertilmicin Sulfate; vertilmicin

IUPAC/Chemical Name: bis((2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4-amino-3-(((2S,3R)-3-amino-6-(1-aminoethyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-6-(ethylamino)-2-hydroxycyclohexyl)oxy)-5-methyl-4-(methylamino)tetrahydro-2H-pyran-3,5-diol) pentakis(sulfate)

InChi Key: YUZKIPGPNSUMPH-LNIIJANASA-N

InChi Code: InChI=1S/2C22H43N5O7.5H2O4S/c2*1-5-27-13-8-12(25)17(33-20-11(24)6-7-14(32-20)10(2)23)15(28)18(13)34-21-16(29)19(26-4)22(3,30)9-31-21;5*1-5(2,3)4/h2*7,10-13,15-21,26-30H,5-6,8-9,23-25H2,1-4H3;5*(H2,1,2,3,4)/t2*10?,11-,12+,13-,15+,16-,17-,18+,19-,20-,21-,22+;;;;;/m11...../s1

SMILES Code: O[C@H]([C@@H](NC)[C@@](CO1)(C)O)[C@H]1O[C@@H]2[C@@H](O)[C@H](O[C@@H]3[C@H](N)CC=C(C(N)C)O3)[C@@H](N)C[C@H]2NCC.O[C@H]([C@@H](NC)[C@@](CO4)(C)O)[C@H]4O[C@@H]5[C@@H](O)[C@H](O[C@@H]6[C@H](N)CC=C(C(N)C)O6)[C@@H](N)C[C@H]5NCC.O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Yuan YZ, Zhang M, Fan XL, Hu CQ, Jin SH, Van Schepdael A, Hoogmartens J, Adams E. Analysis of impurities in vertilmicin sulfate by liquid chromatography ion-trap mass spectrometry. J Pharm Biomed Anal. 2013 Jun;80:1-8. doi: 10.1016/j.jpba.2013.02.026. PubMed PMID: 23518304.

2: Wang J, Wang D, He H, Ni K. Determination of vertilmicin sulfate and its related substances by HPLC-ELSD and HPLC-MS2. J Chromatogr Sci. 2006 Oct;44(9):529-34. PubMed PMID: 17059677.

3: Liu Z, Duan G. Stability indicating reversed-phase ion-pairing liquid chromatographic determination of vertilmicin sulfate as bulk drug and in injections. J Pharm Biomed Anal. 2005 Mar 9;37(3):577-83. PubMed PMID: 15740919.

4: Huang TM, Deng CH, Chen NZ, Liu Z, Duan GL. High performance liquid chromatography for the determination of glucosamine sulfate in human plasma after derivatization with 9-fluorenylmethyl chloroformate. J Sep Sci. 2006 Oct;29(15):2296-302. PubMed PMID: 17120813.