SP-187 HCl
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MedKoo CAT#: 527512

CAS#: 1333144-07-2 (HCl)

Description: SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant than wild-type strains. Growth inhibition by proline analogs was significantly enhanced by increasing the osmotic stress of the medium.


Chemical Structure

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SP-187 HCl
CAS# 1333144-07-2 (HCl)

Theoretical Analysis

MedKoo Cat#: 527512
Name: SP-187 HCl
CAS#: 1333144-07-2 (HCl)
Chemical Formula: C16H34ClNO5
Exact Mass: 319.2359
Molecular Weight: 355.9
Elemental Analysis: C, 54.00; H, 9.63; Cl, 9.96; N, 3.94; O, 22.48

Price and Availability

Size Price Availability Quantity
1.0mg USD 90.0 Ready to ship
5.0mg USD 250.0 Ready to ship
10.0mg USD 450.0 Ready to ship
25.0mg USD 950.0 Ready to ship
50.0mg USD 1650.0 Ready to ship
100.0mg USD 2950.0 Ready to ship
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Related CAS #: 1333144-07-2 (HCl)   615253-61-7 (free base)    

Synonym: SP-187 HCl; SP-187 hydrochloride SP-187; SP187; SP 187; N-9-DNJ; UV-4B; N9DNJ; UV4B; N 9 DNJ; UV 4B; Iminosugar UV 4; MON-DNJ; N-9-Methoxynonyldeoxynojirimycin;

IUPAC/Chemical Name: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol hydrochloride

InChi Key: LQFACEKDJKFAIT-NUSSTLEHSA-N

InChi Code: InChI=1S/C16H33NO5.ClH/c1-22-10-8-6-4-2-3-5-7-9-17-11-14(19)16(21)15(20)13(17)12-18;/h13-16,18-21H,2-12H2,1H3;1H/t13-,14+,15-,16-;/m1./s1

SMILES Code: O[C@@H]1[C@@H](CO)N(CCCCCCCCCOC)C[C@H](O)[C@H]1O.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 355.9 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Sugiura M, Kisumi M. Proline-hyperproducing strains of Serratia marcescens: enhancement of proline analog-mediated growth inhibition by increasing osmotic stress. Appl Environ Microbiol. 1985 Apr;49(4):782-6. PubMed PMID: 2860849; PubMed Central PMCID: PMC238445.

2: Baba E, Nakamura M, Ohkuma K, Kira J, Tanaka Y, Nakano S, Niho Y. A peptide-based human T cell leukemia virus type I vaccine containing T and B cell epitopes that induces high titers of neutralizing antibodies. J Immunol. 1995 Jan 1;154(1):399-412. PubMed PMID: 7527817.