BVT173187

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 531645

CAS#: 1374984-75-4

Description: BVT173187 is a neutrophil formyl peptide receptors (FPR1) inhibitor. BVT173187 may be a therapeutic target for the development of novel drugs that may be used to reduce injuries in inflammatory diseases including asthma, rheumatoid arthritis, Alzheimer's disease and cardiovascular diseases.


Price and Availability

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BVT173187 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 531645
Name: BVT173187
CAS#: 1374984-75-4
Chemical Formula: C14H10Cl3NO2
Exact Mass: 328.9777
Molecular Weight: 330.59
Elemental Analysis: C, 50.86; H, 3.05; Cl, 32.17; N, 4.24; O, 9.68


Synonym: BVT173187; BVT 173187; BVT-173187.

IUPAC/Chemical Name: 3,5-dichloro-N-(2-chloro-5-methylphenyl)-2-hydroxybenzamide

InChi Key: UCOQCHLODZCXRH-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H10Cl3NO2/c1-7-2-3-10(16)12(4-7)18-14(20)9-5-8(15)6-11(17)13(9)19/h2-6,19H,1H3,(H,18,20)

SMILES Code: O=C(NC1=CC(C)=CC=C1Cl)C2=CC(Cl)=CC(Cl)=C2O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1: Cevik-Aras H, Kalderén C, Jenmalm Jensen A, Oprea T, Dahlgren C, Forsman H. A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1. Biochem Pharmacol. 2012 Jun 15;83(12):1655-62. doi: 10.1016/j.bcp.2012.02.024. PubMed PMID: 22410002.