WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 329504
Description: Lanifibranor, also known as IVA-337, is a peroxisome proliferator-activated receptors (PPAR) agonist.
MedKoo Cat#: 329504
Chemical Formula: C19H15ClN2O4S2
Exact Mass: 434.0162
Molecular Weight: 434.909
Elemental Analysis: C, 52.47; H, 3.48; Cl, 8.15; N, 6.44; O, 14.71; S, 14.74
Synonym: Lanifibranor; IVA-337; IVA 337; IVA337.
IUPAC/Chemical Name: 4-(1-(1,3-Benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl)butanoic acid
InChi Key: OQDQIFQRNZIEEJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H15ClN2O4S2/c20-13-4-7-17-12(8-13)9-14(2-1-3-19(23)24)22(17)28(25,26)15-5-6-16-18(10-15)27-11-21-16/h4-11H,1-3H2,(H,23,24)
SMILES Code: O=C(O)CCCC(N1S(=O)(C2=CC=C3N=CSC3=C2)=O)=CC4=C1C=CC(Cl)=C4
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 434.909 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Bruni C, Praino E, Allanore Y, Distler O, Gabrielli A, Iannone F,
Matucci-Cerinic M. Use of biologics and other novel therapies for the treatment
of systemic sclerosis. Expert Rev Clin Immunol. 2016 Dec 12:1-14. [Epub ahead of
print] PubMed PMID: 27899043.