WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530467

CAS#: 376638-65-2

Description: BVT-14225 is a 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor.

Chemical Structure

CAS# 376638-65-2

Theoretical Analysis

MedKoo Cat#: 530467
Name: BVT-14225
CAS#: 376638-65-2
Chemical Formula: C16H20ClN3O3S2
Exact Mass: 401.0635
Molecular Weight: 401.924
Elemental Analysis: C, 47.81; H, 5.02; Cl, 8.82; N, 10.45; O, 11.94; S, 15.95

Price and Availability

Size Price Availability Quantity
100.0mg USD 950.0 2 Weeks
200.0mg USD 1650.0 2 Weeks
500.0mg USD 2650.0 2 Weeks
1.0g USD 3650.0 2 Weeks
2.0g USD 4950.0 2 Weeks
5.0g USD 6850.0 2 Weeks
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Synonym: BVT-14225; BVT 14225; BVT14225.

IUPAC/Chemical Name: 2-(2-((3-chloro-2-methylphenyl)sulfonamido)thiazol-4-yl)-N,N-diethylacetamide


InChi Code: InChI=1S/C16H20ClN3O3S2/c1-4-20(5-2)15(21)9-12-10-24-16(18-12)19-25(22,23)14-8-6-7-13(17)11(14)3/h6-8,10H,4-5,9H2,1-3H3,(H,18,19)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 401.924 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Yoo HH, Kim NS, Kim MJ, Shin D, Shin JG, Kim DH. Enantioselective carbonyl
reduction of eperisone in human liver microsomes. Xenobiotica. 2011
Sep;41(9):758-63. doi: 10.3109/00498254.2011.576277. PubMed PMID: 21623702.

2: Navarrete-Vázquez G, Morales-Vilchis MG, Estrada-Soto S, Ramírez-Espinosa JJ,
Hidalgo-Figueroa S, Nava-Zuazo C, Tlahuext H, Leon-Rivera I, Medina-Franco JL,
López-Vallejo F, Webster SP, Binnie M, Ortiz-Andrade R, Moreno-Diaz H. Synthesis
of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with
11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities.
Eur J Med Chem. 2014 Mar 3;74:179-86. doi: 10.1016/j.ejmech.2013.12.042. PubMed
PMID: 24462849.

3: Vicker N, Su X, Ganeshapillai D, Smith A, Purohit A, Reed MJ, Potter BV. Novel
non-steroidal inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. J
Steroid Biochem Mol Biol. 2007 May;104(3-5):123-9. PubMed PMID: 17482805.


100.0mg / USD 950.0