BVT-14225
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530467

CAS#: 376638-65-2

Description: BVT-14225 is a 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor.


Price and Availability

Size
Price

100mg
USD 950
1g
USD 3650
Size
Price

200mg
USD 1650
2g
USD 4950
Size
Price

500mg
USD 2650
5g
USD 6850

BVT-14225, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 530467
Name: BVT-14225
CAS#: 376638-65-2
Chemical Formula: C16H20ClN3O3S2
Exact Mass: 401.0635
Molecular Weight: 401.924
Elemental Analysis: C, 47.81; H, 5.02; Cl, 8.82; N, 10.45; O, 11.94; S, 15.95


Synonym: BVT-14225; BVT 14225; BVT14225.

IUPAC/Chemical Name: 2-(2-((3-chloro-2-methylphenyl)sulfonamido)thiazol-4-yl)-N,N-diethylacetamide

InChi Key: PNFMZAHWOASGJC-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H20ClN3O3S2/c1-4-20(5-2)15(21)9-12-10-24-16(18-12)19-25(22,23)14-8-6-7-13(17)11(14)3/h6-8,10H,4-5,9H2,1-3H3,(H,18,19)

SMILES Code: O=C(N(CC)CC)CC1=CSC(NS(=O)(C2=CC=CC(Cl)=C2C)=O)=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Yoo HH, Kim NS, Kim MJ, Shin D, Shin JG, Kim DH. Enantioselective carbonyl
reduction of eperisone in human liver microsomes. Xenobiotica. 2011
Sep;41(9):758-63. doi: 10.3109/00498254.2011.576277. PubMed PMID: 21623702.

2: Navarrete-Vázquez G, Morales-Vilchis MG, Estrada-Soto S, Ramírez-Espinosa JJ,
Hidalgo-Figueroa S, Nava-Zuazo C, Tlahuext H, Leon-Rivera I, Medina-Franco JL,
López-Vallejo F, Webster SP, Binnie M, Ortiz-Andrade R, Moreno-Diaz H. Synthesis
of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with
11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities.
Eur J Med Chem. 2014 Mar 3;74:179-86. doi: 10.1016/j.ejmech.2013.12.042. PubMed
PMID: 24462849.

3: Vicker N, Su X, Ganeshapillai D, Smith A, Purohit A, Reed MJ, Potter BV. Novel
non-steroidal inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. J
Steroid Biochem Mol Biol. 2007 May;104(3-5):123-9. PubMed PMID: 17482805.