WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530465

CAS#: 1093757-42-6

Description: UV0155041 is a potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively).

Chemical Structure

CAS# 1093757-42-6

Theoretical Analysis

MedKoo Cat#: 530465
Name: UV-0155041
CAS#: 1093757-42-6
Chemical Formula: C14H15Cl2NO3
Exact Mass: 315.04
Molecular Weight: 316.178
Elemental Analysis: C, 53.18; H, 4.78; Cl, 22.42; N, 4.43; O, 15.18

Price and Availability

Size Price Availability Quantity
100mg USD 850
200mg USD 1550
500mg USD 2150
1g USD 2950
2g USD 4650
5g USD 6850
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Synonym: UV0155041; UV-0155041; UV 0155041.

IUPAC/Chemical Name: cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanecarboxylic acid


InChi Code: InChI=1S/C14H15Cl2NO3/c15-8-5-9(16)7-10(6-8)17-13(18)11-3-1-2-4-12(11)14(19)20/h5-7,11-12H,1-4H2,(H,17,18)(H,19,20)/t11-,12+/m0/s1

SMILES Code: O=C([C@H]1[C@@H](C(NC2=CC(Cl)=CC(Cl)=C2)=O)CCCC1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: Related CAS# 1259372-69-4 (sodium salt) 1093757-42-6 (free acid)

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 316.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Niswender CM, Johnson KA, Weaver CD, Jones CK, Xiang Z, Luo Q, Rodriguez AL,
Marlo JE, de Paulis T, Thompson AD, Days EL, Nalywajko T, Austin CA, Williams MB,
Ayala JE, Williams R, Lindsley CW, Conn PJ. Discovery, characterization, and
antiparkinsonian effect of novel positive allosteric modulators of metabotropic
glutamate receptor 4. Mol Pharmacol. 2008 Nov;74(5):1345-58. doi:
10.1124/mol.108.049551. PubMed PMID: 18664603; PubMed Central PMCID: PMC2574552.