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MedKoo CAT#: 329306

CAS#: 5003-48-5

Description: Benorilate, also known as Win-11450, is an ester of aspirin and paracetamol with analgesic, antipyretic, and anti-inflammatory activity used in the treatment of rheumatoid diseases. Benorilate has less severe side effects than aspirin.

Price and Availability

Size Price Shipping out time Quantity
1g USD 90 2 weeks
2g USD 150 2 weeks
5g USD 250 2 weeks
10g USD 450 2 weeks
25g USD 750 2 weeks
50g USD 1250 2 weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-15. Prices are subject to change without notice.

Benorilate (Win-11450), purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 329306
Name: Benorilate
CAS#: 5003-48-5
Chemical Formula: C17H15NO5
Exact Mass: 313.095
Molecular Weight: 313.309
Elemental Analysis: C, 65.17; H, 4.83; N, 4.47; O, 25.53

Synonym: Benorilate; Win-11450; Win 11450; Win11450; TO 125; TO-125; TO125; Salipran; Fenasparate

IUPAC/Chemical Name: 4-acetamidophenyl 2-acetoxybenzoate


InChi Code: InChI=1S/C17H15NO5/c1-11(19)18-13-7-9-14(10-8-13)23-17(21)15-5-3-4-6-16(15)22-12(2)20/h3-10H,1-2H3,(H,18,19)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Wang CY, Hu XY. Determination of benorilate in pharmaceutical formulations and its metabolite in urine at carbon paste electrode modified by silver nanoparticles. Talanta. 2005 Sep 15;67(3):625-33. doi: 10.1016/j.talanta.2005.03.009. PubMed PMID: 18970216.

2: Chen J, Tu XD. [Studies on formulation and bioavailability of benorilate tablets]. Yao Xue Xue Bao. 1994;29(9):707-12. Chinese. PubMed PMID: 7900541.

3: Jiang JG, Zhang XR, Zhang YH, Song GS. [Rapid identification 15 effective components of anti common cold medicine with MRM by LC-MS/MS]. Yao Xue Xue Bao. 2013 Jan;48(1):94-7. Chinese. PubMed PMID: 23600148.

4: Asch L, Ayrolles C, Serratrice G, Simon L. [Clinical study of benorilate. Co-ordinated multi-centre test (author's transl)]. Sem Hop. 1979 Sep 18-25;55(31-32):1395-9. French. PubMed PMID: 41323.

5: Chevalier G, Rohrbach P, Bollet C, Caude M. [Identification and quantitation of impurities from benorilate (Salipran) by high-performance liquid chromatography (author's transl)]. J Chromatogr. 1977 Aug 1;138(1):193-201. French. PubMed PMID: 19488.

6: Lörincz G, Kary K. [Thermographic and histologic studies of the antiinflammatory effect of benorilate by means of the cotton pellet test in the rat (author's transl)]. Arzneimittelforschung. 1975 Oct;25(10):1549-1. German. PubMed PMID: 1041.

7: De Vries J, Jansen JD, Kroese ED, Van Bree L, Van Ginneken CA. Protection against paracetamol-induced glutathione depletion following a paracetamol-acetylsalicylic acid mixture or benorilate in phenobarbital-treated rats. Toxicol Lett. 1981 Dec;9(4):345-7. PubMed PMID: 6120590.

8: Melikhova NI, Klimov IuV. [Clinical evaluation of the effectiveness of benorilate in rheumatoid arthritis in children]. Pediatriia. 1980;(9):52-3. Russian. PubMed PMID: 6107892.

9: de Vries J. Hepatotoxic metabolic activation of paracetamol and its derivatives phenacetin and benorilate: oxygenation or electron transfer? Biochem Pharmacol. 1981 Mar 1;30(5):399-402. PubMed PMID: 6112004.

10: Gao Y, Xu J, Xu J, Huang Y, Shen Y, Liu Z. A rapid and sensitive LC-MS/MS assay for the quantitation of deacetyl mycoepoxydiene in rat plasma with application to preclinical pharmacokinetics studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jan 1;880(1):1-5. doi: 10.1016/j.jchromb.2011.06.044. PubMed PMID: 22169059.

11: Reiter W. [Long-term toxicity of benorylate]. Z Rheumatol. 1975 Jul-Aug;34(7-8):270-5. German. PubMed PMID: 241174.

12: Marzo A, Quadro G, Treffner E, Ripamonti M, Meroni G, Lucarelli C. High-pressure liquid chromatographic evaluation of cyclic paracetamol-acetylsalicylate and its active metabolites with results of a comparative pharmacokinetic investigation in the rat. Arzneimittelforschung. 1990 Jul;40(7):813-7. PubMed PMID: 1977396.

13: Barasoain I, Rojo JM, Portolés A. "In vivo" effects of acetylsalicylic acid and two ether derived compounds on primary immune response and lymphoblastic transformation. Immunopharmacology. 1980 Dec;2(4):293-300. PubMed PMID: 6109698.

14: Palme G, Koeppe P. [Comparative experimental studies in animals and humans on gastrointestinal blood loss following antirheumatic pharmacotherapy (author's transl)]. Arzneimittelforschung. 1978;28(3):426-8. German. PubMed PMID: 26360.