Gemcabene calcium

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MedKoo CAT#: 525160

CAS#: 209789-08-2 (calcium)

Description: Gemcabene is a lipid-lowering small molecule to be used as an adjunctive therapy to reduce LDL-C, hsCRP, and TGs. Gemcabene is a first-in-class oral drug candidate with pleiotropic properties similar to statins as shown in trials to date. Gemcabene has a unique mechanism of action that involves the: (1) blocking the production of hepatic triglyceride and cholesterol synthesis; and (2) enhancing the clearance of VLDL by decreasing ApoC-III.

Chemical Structure

Gemcabene calcium
CAS# 209789-08-2 (calcium)

Theoretical Analysis

MedKoo Cat#: 525160
Name: Gemcabene calcium
CAS#: 209789-08-2 (calcium)
Chemical Formula: C16H28CaO5
Exact Mass: 302.21
Molecular Weight: 340.470
Elemental Analysis: C, 56.44; H, 8.29; Ca, 11.77; O, 23.50

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

Related CAS #: 209789-08-2 (calcium), 183293-82-5 (free base),

Synonym: Gemcabene; Gemcabene [INN]; PD 72953; PD-72953.

IUPAC/Chemical Name: calcium 6,6'-oxybis(2,2-dimethylhexanoate)


InChi Code: InChI=1S/C16H30O5.Ca/c1-15(2,13(17)18)9-5-7-11-21-12-8-6-10-16(3,4)14(19)20;/h5-12H2,1-4H3,(H,17,18)(H,19,20);/q;+2/p-2

SMILES Code: O=C([O-])C(C)(C)CCCCOCCCCC(C)(C)C([O-])=O.[Ca+2]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 340.470000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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