Bioconjugate Synthesis

Medkoo offers a variety of custom labeling and synthesis services to assist scientists with unmet needs or requirements that go beyond our basic offerings. Based on our many years of experience in dye conjugation, our custom services provide a unique solution for most custom needs.


Medkoo offers a full spectrum of high quality, custom bioconjugation reagent systems as well as custom synthesis and functionalized biomolecules ready to be cross-linked. These biomolecules can be modified and linked to one or several biomolecules via homobifunctional or heterobifunctional cross-linking chemistries. Our expertise and experience in medicinal and bioconjugation chemistries has assisted our clients from project scope collection to design of appropriate conjugation schemes. We have delivered thousands of custom conjugated biopolymers. We are fully capable of meeting the ever-increasing bioconjugation needs of our clients by aggressively seeking to develop new methodologies that assist our clients to develop new bioconjugate reagents for their biological and drug discovery research.


MedKoo not only offers synthesis of small molecule and biopolymers, but also assists in the functionalization or activation of compounds ready to cross link with pre-activated small molecules either supplied by customers or prepared in-house. These pre-activated small molecules can be created with an amine, acid, hydrazine, aldehyde/ketone, hydroxylamine, maleimide/alkylhalide, and sulfhydryl functional group in a polymer. After labeling of biopolymer with small molecules, a standard desalting, purification, quality check and final concentration and labeling ratio are determined.


Custom Options:


Infrared and visible Dye Labeling

  • • Antibodies
  • • Proteins
  • • Peptides
  • • Enzymes
  • • Small Molecules
  • • Lectins
  • • Water Soluble Polymers
  • • Nanoparticles

Custom Derivation of Fluorescent Dyes

  • • NHS Ester
  • • Maleimide
  • • Azide
  • • Alkyne
  • • DBCO
  • • Hydrazide
  • • Amine
  • • Others