WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 206195
Description: INCB054828 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) types 1, 2, and 3 (FGFR1/2/3), with potential antineoplastic activity. FGFR inhibitor INCB054828 binds to and inhibits FGFR1/2/3, which may result in the inhibition of FGFR1/2/3-related signal transduction pathways. This inhibits proliferation in FGFR1/2/3-overexpressing tumor cells. FGFR, a family of receptor tyrosine kinases upregulated in many tumor cell types, plays a key role in cellular proliferation, migration, and survival. Check for active clinical trials or closed clinical trials using this agent.
MedKoo Cat#: 206195
Synonym: INCB054828; INCB-054828; INCB 054828; INCB54828; INCB 54828; INCB-54828.
IUPAC/Chemical Name: NONE