2'-Deoxyadenosine-5'-Monophosphate, Free acid
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 122552

CAS#: 653-63-4

Description: 2'-deoxyadenosine 5'-monophosphate is a purine 2'-deoxyribonucleoside 5'-monophosphate having adenine as the nucleobase. It has a role as a fundamental metabolite.

Chemical Structure

img
2'-Deoxyadenosine-5'-Monophosphate, Free acid
CAS# 653-63-4
Instruction

Theoretical Analysis

MedKoo Cat#: 122552
Name: 2'-Deoxyadenosine-5'-Monophosphate, Free acid
CAS#: 653-63-4
Chemical Formula: C10H14N5O6P
Exact Mass: 331.07
Molecular Weight: 331.220
Elemental Analysis: C, 36.26; H, 4.26; N, 21.14; O, 28.98; P, 9.35

Price and Availability

Size Price Availability Quantity
250mg USD 350 2 Weeks
1g USD 750 2 Weeks
Bulk inquiry

Synonym: 653-63-4; 2'-deoxyadenosine-5'-monophosphate; dAMP; 2'-Deoxyadenosine 5'-monophosphate; 2'-Deoxyadenylic acid

IUPAC/Chemical Name: ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

InChi Key: KHWCHTKSEGGWEX-RRKCRQDMSA-N

InChi Code: InChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1

SMILES Code: O[C@@H](C[C@H](N1C=NC2=C(N=CN=C21)N)O3)[C@H]3COP(O)(O)=O

Appearance: To be determined

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 331.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Petroselli G, Erra-Balsells R, Cabrerizo FM, Lorente C, Capparelli AL, Braun
AM, Oliveros E, Thomas AH. Photosensitization of
2'-deoxyadenosine-5'-monophosphate by pterin. Org Biomol Chem. 2007 Sep
7;5(17):2792-9. doi: 10.1039/b707312g. Epub 2007 Jul 19. PMID: 17700847.

2: Chiavarino B, Crestoni ME, Fornarini S, Scuderi D, Salpin JY. Undervalued N3
Coordination Revealed in the Cisplatin Complex with
2'-Deoxyadenosine-5'-monophosphate by a Combined IRMPD and Theoretical Study.
Inorg Chem. 2017 Aug 7;56(15):8793-8801. doi: 10.1021/acs.inorgchem.7b00570.
Epub 2017 Jul 18. PMID: 28718635.

3: Wu RR, He CC, Hamlow LA, Nei YW, Berden G, Oomens J, Rodgers MT. N3
Protonation Induces Base Rotation of 2'-Deoxyadenosine-5'-monophosphate and
Adenosine-5'-monophosphate. J Phys Chem B. 2016 May 26;120(20):4616-24. doi:
10.1021/acs.jpcb.6b04052. Epub 2016 May 17. PMID: 27138137.