Chloroxylenol | CAS# 88-04-0 | Topical antiseptic

Chloroxylenol
featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 413582

CAS#: 88-04-0

Description: Chloroxylenol is a topical antiseptic.

Chemical Structure

Chloroxylenol

CAS# 88-04-0

Instruction

Theoretical Analysis

MedKoo Cat#: 413582
Name: Chloroxylenol
CAS#: 88-04-0
Chemical Formula: C8H9ClO
Exact Mass: 156.03
Molecular Weight: 156.610
Elemental Analysis: C, 61.36; H, 5.79; Cl, 22.64; O, 10.22

Price and Availability

Size	Price	Availability	Quantity
10g	USD 250	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Chloroxylenol; HSDB7427; HSDB-7427; HSDB 7427; 4-Chloro-3,5-dimethylphenol

IUPAC/Chemical Name: 4-chloro-3,5-dimethylphenol

InChi Key: OSDLLIBGSJNGJE-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H9ClO/c1-5-3-7(10)4-6(2)8(5)9/h3-4,10H,1-2H3

SMILES Code: Cc1c(Cl)c(C)cc(O)c1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 156.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Wilson M, Mowad C. Chloroxylenol. Dermatitis. 2007 Jun;18(2):120-1. PMID: 17498419.

2: Poger D, Mark AE. Effect of Triclosan and Chloroxylenol on Bacterial Membranes. J Phys Chem B. 2019 Jun 27;123(25):5291-5301. doi: 10.1021/acs.jpcb.9b02588. Epub 2019 Jun 18. PMID: 31242742.

3: Wood A, Payne D. The action of three antiseptics/disinfectants against enveloped and non-enveloped viruses. J Hosp Infect. 1998 Apr;38(4):283-95. doi: 10.1016/s0195-6701(98)90077-9. PMID: 9602977; PMCID: PMC7134397.

4: Choi D, Oh S. Removal of Chloroxylenol Disinfectant by an Activated Sludge Microbial Community. Microbes Environ. 2019 Jun 27;34(2):129-135. doi: 10.1264/jsme2.ME18124. Epub 2019 Feb 23. PMID: 30799319; PMCID: PMC6594741.

5: Dellanno C, Vega Q, Boesenberg D. The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus. Am J Infect Control. 2009 Oct;37(8):649-52. doi: 10.1016/j.ajic.2009.03.012. Epub 2009 Aug 18. PMID: 19692148; PMCID: PMC7132643.

6: Mehrtens SH, Reckling C. Contact urticaria with anaphylaxis caused by chlorocresol, chloroxylenol, and thiourea. Contact Dermatitis. 2019 May;80(5):311-313. doi: 10.1111/cod.13194. Epub 2019 Jan 9. PMID: 30523628.

7: Rundle CW, Hu S, Presley CL, Dunnick CA. Triclosen and Its Alternatives in Antibacterial Soaps. Dermatitis. 2019 Nov/Dec;30(6):352-357. doi: 10.1097/DER.0000000000000519. PMID: 31688130.

8: Orazi G, Ruoff KL, O'Toole GA. Pseudomonas aeruginosa Increases the Sensitivity of Biofilm-Grown Staphylococcus aureus to Membrane-Targeting Antiseptics and Antibiotics. mBio. 2019 Jul 30;10(4):e01501-19. doi: 10.1128/mBio.01501-19. PMID: 31363032; PMCID: PMC6667622.

9: Yost LJ, Rodricks JD, Turnbull D, DeLeo PC, Nash JF, Quiñones-Rivera A, Carlson PA. Human health risk assessment of chloroxylenol in liquid hand soap and dishwashing soap used by consumers and health-care professionals. Regul Toxicol Pharmacol. 2016 Oct;80:116-24. doi: 10.1016/j.yrtph.2016.06.003. Epub 2016 Jun 15. PMID: 27316554.

10: Zhou Y, Cheng G, Chen K, Lu J, Lei J, Pu S. Adsorptive removal of bisphenol A, chloroxylenol, and carbamazepine from water using a novel β-cyclodextrin polymer. Ecotoxicol Environ Saf. 2019 Apr 15;170:278-285. doi: 10.1016/j.ecoenv.2018.11.117. Epub 2018 Dec 7. PMID: 30529923.

Your view history

Chloroxylenol featured