ML-030
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530919

CAS#: 1013750-77-0

Description: ML-030, also known as CID-11757146, is a potent and selective PDE4 inhibitor. ML-030 inhibits PDE4 in a cell-based cyclic nucleotide-gated cation channel biosensor assay with an EC50 value of 18.7 nM.


Price and Availability

Size
Price

100mg
USD 1350
1g
USD 3650
Size
Price

200mg
USD 1950
2g
USD 5450
Size
Price

500mg
USD 2650
5g
Ask price

ML-030, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 530919
Name: ML-030
CAS#: 1013750-77-0
Chemical Formula: C20H20N4O4S
Exact Mass: 412.1205
Molecular Weight: 412.464
Elemental Analysis: C, 58.24; H, 4.89; N, 13.58; O, 15.52; S, 7.77


Synonym: ML-030; ML 030; ML030; CID-11757146; CID 11757146; CID11757146.

IUPAC/Chemical Name: 3-(2,5-dimethoxyphenyl)-6-(3,4-dimethoxyphenyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazine

InChi Key: DZAUSKKPHXFGNN-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H20N4O4S/c1-25-13-6-8-16(26-2)14(10-13)19-21-22-20-24(19)23-15(11-29-20)12-5-7-17(27-3)18(9-12)28-4/h5-10H,11H2,1-4H3

SMILES Code: COC1=CC=C(C2=NN3C(SC2)=NN=C3C4=CC(OC)=CC=C4OC)C=C1OC


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


Additional Information

Type 4 cyclic nucleotide phosphodiesterases (PDE4s), which are highly expressed in neutrophils and monocytes, selectively inactivate the second messenger cAMP by hydrolyzing the phosphodiester bond, producing AMP.