SF2523
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 206841

CAS#: 1174428-47-7

Description: SF2523 is a highly selective and potent dual pan-PI3K/BRD4 inhibitor. SF2523 exhibits a remarkable kinase selectivity inhibiting potently only 4 out of the 232 non-PI3K kinases at the enzyme level, showing broad potency against 19 cancer cell lines in vitro, and exhibiting potent in vivo anti- tumor activity in xenograft studies. SF2523 exhibits demonstrated anti- cancer stem cell and generation of oxidative stress activities. The biological, chemical, and computational profile of SF2523 have been published in J. Med. Chem. 2013, Vol. 56, pages 1922-1939 (doi: 10.1021/jm301522m).


Price and Availability

Size
Price

10mg
USD 150
100mg
USD 750
1g
USD 3250
Size
Price

25mg
USD 250
200mg
USD 1050
2g
USD 5250
Size
Price

50mg
USD 450
500mg
USD 1750
5g
USD 7850

SF2523, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 206841
Name: SF2523
CAS#: 1174428-47-7
Chemical Formula: C19H17NO5S
Exact Mass: 371.0827
Molecular Weight: 371.407
Elemental Analysis: C, 61.44; H, 4.61; N, 3.77; O, 21.54; S, 8.63


Synonym: SF2523; SF-2523; SF 2523.

IUPAC/Chemical Name: 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-morpholino-7H-thieno[3,2-b]pyran-7-one

InChi Key: BYTKNUOMWLJVNQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H17NO5S/c21-14-10-17(20-3-5-22-6-4-20)25-18-13(11-26-19(14)18)12-1-2-15-16(9-12)24-8-7-23-15/h1-2,9-11H,3-8H2

SMILES Code: O=C1C=C(N2CCOCC2)OC3=C1SC=C3C4=CC=C(OCCO5)C5=C4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490