WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 525943
Description: DBPR211, also known as CB1-IN-1, is a novel potent CB1 receptor agonist. DBPR211 possesses an extremely low brain to plasma ratio. It significantly improves insulin resistance in diabetic models, and induces weight loss and decreases hepatic steatosis as well as insulin resistance in obese model. This drug candidate is well protected by various global patent applications. IBPR/NHRI will seek for industrial partner to further develop DBPR211, and clinical trials will be conducted after technical transfer in the near future.
MedKoo Cat#: 525943
Chemical Formula: C33H31Cl2F3N6O3S2
Exact Mass: 750.1228
Molecular Weight: 751.6652
Elemental Analysis: C, 52.73; H, 4.16; Cl, 9.43; F, 7.58; N, 11.18; O, 6.39; S, 8.53
Synonym: DBPR211; DBPR 211; DBPR-211; CB1-IN-1; CB1-IN 1; CB1-IN1;
IUPAC/Chemical Name: 1-(2,4-Dichloro-phenyl)-4-[(pyrrolidine-1-sulfonylamino)-methyl]-5-[5-(4-trifluoromethyl-phenylethynyl)-thiophen-2-yl]-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide
InChi Key: KAIYFJUWIBTYPK-UHFFFAOYSA-N
InChi Code: InChI=1S/C33H31Cl2F3N6O3S2/c34-24-11-14-28(27(35)20-24)44-31(29-15-13-25(48-29)12-8-22-6-9-23(10-7-22)33(36,37)38)26(21-39-49(46,47)43-18-4-5-19-43)30(40-44)32(45)41-42-16-2-1-3-17-42/h6-7,9-11,13-15,20,39H,1-5,16-19,21H2,(H,41,45)
SMILES Code: O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(C#CC4=CC=C(C(F)(F)F)C=C4)S3)=C1CNS(=O)(N5CCCC5)=O)NN6CCCCC6