2,2'-Bipyridine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525738

CAS#: 366-18-7

Description: 2,2'-Bipyridine is a universal activator of miRNAs, which modulated miRNA expression levels by promoting the processing of miRNA precursors.


Price and Availability

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2,2'-Bipyridine is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525738
Name: 2,2'-Bipyridine
CAS#: 366-18-7
Chemical Formula: C10H8N2
Exact Mass: 156.0687
Molecular Weight: 156.188
Elemental Analysis: C, 76.90; H, 5.16; N, 17.94


Synonym: 2,2'-Bipyridine

IUPAC/Chemical Name: 2,2'-Dipyridine

InChi Key: ROFVEXUMMXZLPA-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H

SMILES Code: C1(C2=NC=CC=C2)=NC=CC=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

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2: Shalan H, Colbert A, Nguyen TT, Kato M, Cheruzel L. Correlating the para-Substituent Effects on Ru(II)-Polypyridine Photophysical Properties and on the Corresponding Hybrid P450 BM3 Enzymes Photocatalytic Activity. Inorg Chem. 2017 May 24. doi: 10.1021/acs.inorgchem.7b00685. [Epub ahead of print] PubMed PMID: 28537742.

3: Phapale D, Ghosh R, Das D. Solvent- and DNA-Controlled Phototriggered Linkage Isomerization in a Ruthenium Sulfoxide Complex Incorporating Dipyrido[3,2-a:2',3'-c]phenazine (dppz). Inorg Chem. 2017 May 24. doi: 10.1021/acs.inorgchem.7b00412. [Epub ahead of print] PubMed PMID: 28537408.

4: Shahroosvand H, Abaspour S, Pashaei B, Radicchi E, De Angelis F, Bonaccorso F. A ruthenium tetrazole complex-based high efficiency near infrared light electrochemical cell. Chem Commun (Camb). 2017 May 23. doi: 10.1039/c7cc02878d. [Epub ahead of print] PubMed PMID: 28534893.

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6: Álvarez D, Mera-Adasme R, Riera L, Cárdenas-Jirón GI, Pérez J, Díaz J, Menéndez MI, López R. Insights on the Reactivity of Terminal Phosphanido Metal Complexes toward Activated Alkynes from Theoretical Computations. Inorg Chem. 2017 May 18. doi: 10.1021/acs.inorgchem.7b00767. [Epub ahead of print] PubMed PMID: 28520424.

7: Nastasi F, La Ganga G, Campagna S, Syrgiannis Z, Rigodanza F, Vitale S, Licciardello A, Prato M. Multichromophoric hybrid species made of perylene bisimide derivatives and Ru(ii) and Os(ii) polypyridine subunits. Phys Chem Chem Phys. 2017 May 18. doi: 10.1039/c7cp01597f. [Epub ahead of print] PubMed PMID: 28518200.

8: Tang B, Wan D, Lai SH, Yang HH, Zhang C, Wang XZ, Zeng CC, Liu YJ. Design, synthesis and evaluation of anticancer activity of ruthenium (II) polypyridyl complexes. J Inorg Biochem. 2017 May 10;173:93-104. doi: 10.1016/j.jinorgbio.2017.04.028. [Epub ahead of print] PubMed PMID: 28511064.

9: Zahariou G. Characterization of the High-Spin Co(II) Intermediate Species of the O(2)-Evolving Co(4)O(4) Cubic Molecules. Inorg Chem. 2017 May 16. doi: 10.1021/acs.inorgchem.7b00079. [Epub ahead of print] PubMed PMID: 28509540.

10: Singha K, Laha P, Chandra F, Dehury N, Koner AL, Patra S. Long-Lived Polypyridyl Based Mononuclear Ruthenium Complexes: Synthesis, Structure, and Azo Dye Decomposition. Inorg Chem. 2017 May 16. doi: 10.1021/acs.inorgchem.7b00536. [Epub ahead of print] PubMed PMID: 28509536.

11: Brown ML, Ovens JS, Leznoff DB. Dicyanoaurate-based heterobimetallic uranyl coordination polymers. Dalton Trans. 2017 May 16. doi: 10.1039/c7dt00942a. [Epub ahead of print] PubMed PMID: 28508898.

12: Kagalwala HN, Chirdon DN, Mills IN, Budwal N, Bernhard S. Light-Driven Hydrogen Generation from Microemulsions Using Metallosurfactant Catalysts and Oxalic Acid. Inorg Chem. 2017 May 10. doi: 10.1021/acs.inorgchem.7b00463. [Epub ahead of print] PubMed PMID: 28488856.

13: Ji Y, Lee HJ, Kim M, Nam G, Lee SJC, Cho J, Park CM, Lim MH. Strategic Design of 2,2'-Bipyridine Derivatives to Modulate Metal-Amyloid-β Aggregation. Inorg Chem. 2017 May 9. doi: 10.1021/acs.inorgchem.7b00782. [Epub ahead of print] PubMed PMID: 28485587.

14: Boulsourani Z, Katsamakas S, Geromichalos GD, Psycharis V, Raptopoulou CP, Hadjipavlou-Litina D, Yiannaki E, Dendrinou-Samara C. Synthesis, structure elucidation and biological evaluation of triple bridged dinuclear copper(II) complexes as anticancer and antioxidant/anti-inflammatory agents. Mater Sci Eng C Mater Biol Appl. 2017 Jul 1;76:1026-1040. doi: 10.1016/j.msec.2017.03.157. Epub 2017 Mar 22. PubMed PMID: 28482466.

15: Wang Y, Rinkevicius Z, Ahlquist MSG. Formation of N-oxide in the third oxidation of [Ru(II)(tpy)(L)(OH(2))](2). Chem Commun (Camb). 2017 May 18;53(41):5622-5624. doi: 10.1039/c7cc03041j. PubMed PMID: 28480458.

16: Wan D, Lai SH, Zeng CC, Zhang C, Tang B, Liu YJ. Ruthenium(II) polypyridyl complexes: Synthesis, characterization and anticancer activity studies on BEL-7402 cells. J Inorg Biochem. 2017 Apr 27;173:1-11. doi: 10.1016/j.jinorgbio.2017.04.026. [Epub ahead of print] PubMed PMID: 28472754.

17: Sampaio RN, Müller AV, Polo AS, Meyer GJ. Correlation Between Charge Recombination and Lateral Hole-Hopping Kinetics in a Series of cis-Ru(phen')(dcb)(NCS)(2) Dye-Sensitized Solar Cells. ACS Appl Mater Interfaces. 2017 May 4. doi: 10.1021/acsami.7b01542. [Epub ahead of print] PubMed PMID: 28471164.

18: Kong YJ, Li P, Han LJ, Fan LT, Li PP, Yin S. Two cadmium(II) fluorous coordination compounds tuned by different bipyridines. Acta Crystallogr C Struct Chem. 2017 May 1;73(Pt 5):424-429. doi: 10.1107/S2053229617006003. Epub 2017 Apr 26. PubMed PMID: 28469070.

19: Kuramochi Y, Sekine M, Kitamura K, Maegawa Y, Goto Y, Shirai S, Inagaki S, Ishida H. Photocatalytic CO2 Reduction by Periodic Mesoporous Organosilica (PMO) Containing Two Different Ruthenium Complexes as Photosensitizing and Catalytic Sites. Chemistry. 2017 May 3. doi: 10.1002/chem.201701466. [Epub ahead of print] PubMed PMID: 28467639.

20: Ruan R, Wang M, Liu X, Sun X, Chung KR, Li H. Functional analysis of two sterol regulatory element binding proteins in Penicillium digitatum. PLoS One. 2017 May 3;12(5):e0176485. doi: 10.1371/journal.pone.0176485. eCollection 2017. PubMed PMID: 28467453; PubMed Central PMCID: PMC5415137.