Uramustine | Uracil mustard | CAS#66-75-1

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MedKoo product information:

Uramustine

Description of Uramustine: Uramustine (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects. Chemically it is a derivative of nitrogen mustard and uracil. (source: http://en.wikipedia.org/wiki/Uramustine).

MedKoo Code#: 100900

Name: Uramustine

CAS#: 66-75-1

Synonym: uracil mustard; Demethyldopan, Desmethyldopan, Uracilmostaza, Uracillost, Uramustin, Nordopan, Chlorethaminacil, Aminouracil mustard, Uramustina, Uramustinum, Uracil lost, Uracil nitrogen mustard, 5-Aminouracil mustard, Uramustine (INN), Uracil lost [German], Uracil mustard (TN), Uramustinum [INN-Latin], Uramustina [INN-Spanish]

IUPAC/Chemical name:

5-[bis(2-chloroethyl)amino]-1H-pyrimidine-2,4-dione

Chemical structure:

Theoretical analysis :

MedKoo Code#: 100900
Name: Uramustine
CAS#: 66-75-1

Chemical Formula: C8H11Cl2N3O2

Exact Mass: 251.02283

Molecular Weight: 252.09784

Elemental Analysis: C, 38.11; H, 4.40; Cl, 28.13; N, 16.67; O, 12.69

Availability and price:

Uramustine (uracil mustard) (98%) is in stock (price reduced on 8/25/2012)

10 mg / $150.00
20 mg / $220.00
50 mg / $350.00
100 mg / $450.00
200 mg / $550.00
500 mg / $750.00
Multiple grams in stock at low price.

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Quality control data:

Product will be shipped with supporting analytical data.

Information about this agent

Uramustine (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects. Chemically it is a derivative of nitrogen mustard and uracil.

References

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