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MedKoo product information:
Fotemustine
Fotemustine is a chloroethylating
nitrosourea with antineoplastic activity. Fotemustine alkylates
guanine by forming chloroethyl adducts at the 6 position of guanine,
resulting in N1-guanine and N3-cytosine cross linkages, inhibition
of DNA synthesis, cell cycle arrest, and finally apoptosis. This
agent is lipophilic and crosses the blood-brain barrier. Check for
active clinical trials or
closed clinical trials using this agent. (NCI
Thesaurus).
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MedKoo Code#: 100384
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Name:
Fotemustine
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CAS#:
92118-27-9
Synonym: Foreign
brand name: Muphoran. Code name: S 10036.
IUPAC/Chemical name:
diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate
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Chemical structure:
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Theoretical analysis
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Chemical Formula: C9H19ClN3O5P
Exact Mass: 315.07508
Molecular Weight: 315.69
Elemental Analysis: C, 34.24; H, 6.07; Cl,
11.23; N, 13.31; O, 25.34; P, 9.81
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Availability and price:
Fotemustine
is available through custom synthesis
For quotation, question, and order, please send email to
sales@medkoo.com to describe your needs. A representative
will respond your email shortly. We offer significant discount
for larger quantity order.
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Quality control
data:
Product will be shipped with
supporting analytical data.
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Information about this agent
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Contact MedKoo:
Email:
sales@medkoo.com
(Keyword; CAS#; MedKoo code#)
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